Understanding Sex Hormone-Binding Globulin (SHBG)

Sex Hormone-Binding Globulin (SHBG) is a key biomarker in blood tests that shbg binds to sex hormones, regulating their bioavailability.

What is Sex Hormone-Binding Globulin?

SHBG binds to sex hormones, regulating their bioavailability.

Normal Range

Low < 10 nmol/L
Normal 10 - 57 nmol/L
High > 57 nmol/L

The normal Sex Hormone-Binding Globulin range is between 10.0 and 57.0 nmol/L.

High Sex Hormone-Binding Globulin Levels (Above 57.0 nmol/L)

Causes of High Sex Hormone-Binding Globulin

High SHBG can be caused by hyperthyroidism, liver disease, or estrogen excess. Balancing thyroid function and hormone levels can help regulate SHBG.

Health Effects of High Sex Hormone-Binding Globulin

High SHBG may lower bioavailable testosterone and estrogen, contributing to fatigue, muscle weakness, reduced libido, and hormonal imbalance.

Low Sex Hormone-Binding Globulin Levels (Below 10.0 nmol/L)

Causes of Low Sex Hormone-Binding Globulin

Low SHBG is linked to insulin resistance, obesity, and metabolic disorders. Weight loss and increased fiber intake can help improve SHBG levels.

Health Effects of Low Sex Hormone-Binding Globulin

Low SHBG increases free androgens, which can contribute to acne, hair loss, and metabolic syndrome.

Treatment and Management

For High Sex Hormone-Binding Globulin

  • Medical evaluation to determine the underlying cause
  • Lifestyle modifications as recommended by your healthcare provider
  • Regular monitoring of Sex Hormone-Binding Globulin levels
  • Follow-up testing as needed

For Low Sex Hormone-Binding Globulin

  • Medical evaluation to identify the root cause
  • Appropriate supplementation if recommended
  • Dietary changes as advised
  • Regular monitoring and follow-up

When to See a Doctor

Consult your healthcare provider if:

  • Your Sex Hormone-Binding Globulin levels are consistently outside the normal range
  • You experience symptoms associated with abnormal Sex Hormone-Binding Globulin levels
  • You have risk factors for conditions affecting Sex Hormone-Binding Globulin levels
  • You’re taking medications that may affect Sex Hormone-Binding Globulin levels

Prevention

  • Regular health check-ups
  • Balanced diet
  • Regular exercise
  • Stress management
  • Adequate sleep
  • Avoiding known triggers

Additional Information

For more detailed information about managing your Sex Hormone-Binding Globulin levels, consult with your healthcare provider or visit reputable medical websites.